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FlexEze Heat Wraps have been active in clinical trials at major Australian hospitals. Follow links below to view studies of the benefits of heat therapy.


  1. American College of Physicians Treatment Guidelines for Acute and Chronic Back Pain 2017

  2. Should I apply heat or ice for my back pain, Doctor?

  3. Flexeze now shown in research to be as effective as ibuprofen and paracetamol for relief of period pain.
    Researchers have recently studied the benefits of a heat patch applied to the lower abdomen. The results of two studies demonstrated the heat patch to be as effective as ibuprofen and paracetamol in relieving the pain associated with muscle spasm and cramping during menstruation.

  4. Paracetamol Is useless for Back Pain: Associate professor Christine Lin, of the Oxford-based George Institute for Global Health, the senior author of the paper, said "people with back pain, would be better off being as active as possible, avoiding bed rest, using heat wraps or heat packs and considering spinal manipulation".

  5. In-situ studies of cartilage microtribology: roles of speed and contact area

  6. E.D. Bonnevie, V. Baro, L. Wang, and D.L. Burris*  Department of Mechanical Engineering, University of Delaware, Newark, DE

  7. Tribological rehydration of cartilage and its potential role in preserving joint health
    A.C. Moore y, D.L. Burris y z *
    y Department of Biomedical Engineering, University of Delaware, Newark, DE, USA
    z Department of Mechanical Engineering, University of Delaware, Newark, DE, USA

  8. Period Pain
    Continuous, low-level, topical heat therapy was superior to Acetaminophen (Paracetamol) for the treatment of dysmenorrhea (period pain)
    Journal:J Reprod Med. 2004 Sep;49(9):739-45.

  9. Heat wrap therapy increases healing of back and knee injury Continuous Low Level Heat Wraps; Faster Healing and Pain Relief during Rehabilitation for Back, Knee and Neck Injuries Jerrold Petrofsky1,*, Michael Laymon2 , Faris Alshammari1 , Iman Akef Khowailed2 , Haneul Lee

  10. A Cochrane review of superficial heat or cold for low back pain. OBJECTIVE: To assess the effects of superficial heat and cold therapy for low back pain in adults.

  11. An exploratory workplace study to investigate the perceived value of continuous low-level heatwrap therapy in manual workers.
    Between 60 and 80% of the population in industrialized countries experience low back pain at some time in their lives. The physical demands of work, i.e. manual handling, lifting, bending, twisting, arkward postures and whole body vibration are associated with low back symptoms. This study was undertaken to investigate the benefits of a new form of continuous low-level heat wrap therapy available for the symptomatic relief of acute low back pain in the workplace.

  12. NHMRC: National Health and Medical Research Council. Clinicians guidelines for the treatment of acute musculoskeletal pain. 
    Impact of continuous low level heatwrap therapy in acute low back pain patients. Muscular pain is usually associated with increased muscle tension resulting in a vicious tension-pain-cycle, leading to increased alertness and stress.

  13. New developments in the use of Heat Therapy for back pain
    Recent advances in the understanding and use of heat therapy for treatment of back pain has resulted in the development of FLEXEZE HEAT WRAP THERAPY.

  14. Increased intramuscular and intracapsular temperature via ThermaCare Knee Wrap application. 
    Knee pain is common among the physically active as well as the older population. Heat is often used to decrease pain in these individuals. Modalities such as hot packs and whirlpools increase tissue temperature, yet are not portable. The portable ThermaCare HeatWrap for the knee has recently been marketed.

  15. Managing low back pain in primary care
    The majority of adults with low back pain can be effectively managed in primary care. Routine imaging and bed rest are best avoided. Instead patients should initially be provided with advice and simple analgesics and encouraged to remain as active as possible.  Evidence supports the use of heat packs or wraps which can be bought from pharmacy and are relatively cheap option that patient can use to self manage their pain. Chris G Maher, Director1 and Professor of Physiotherapy,2 Chris Williams, PhD student,1 Chris Lin, Research fellow,1,2 and Jane Latimer, Senior research fellow1 and Associate professor2 1. The George Institute for Global Health, Sydney   2. The University of Sydney

  16. A Pilot study using blood biomarkers and Physiological parameters to asses Thermacare heat wraps for efficacy and timing of application to reduce delayed onset muscle soreness from exercise Flexeze is using an ancient therapy to tackle back pain
    Heat has been used in many forms to provide relief from back pain since the beginning of time. Now Flexeze has brought this age old therapy into the 21st Century with the use of low-level continuous heat wrap therapy.

  17. The new 2010 3rd edition of Acute Pain Management: Scientific Evidence by Australian and New Zealand College of Anaesthetists (ANZCA)
    There is moderate evidence from four trials that heat wrap therapy results in a small short-term reduction in pain in patients with acute or sub-acute low-back pain (French et al, 2006) Level 1 evidence.” “… no good quality evidence for use of cold in the treatment of low back pain ( French et al, 2006) Level 1 evidence.” Quotes Chapter Eight -, 8.4.2    Heat and cold Research conducted in United States has shed light on a new approach to dealing with muscle soreness after exercise, commonly known as delayed onset muscle soreness

  18. Back Pain
    Continuous low-level heat wrap therapy was superior to both acetaminophen (Paracetamol) and ibuprofen for treating low back pain
    Journal:Spine. 2002 May 15;27(10):1012-7

  19. Combining continuous low-level heat wrap therapy with directional preference-based exercise during the treatment of acute low back pain significantly improves functional outcomes compared with either intervention alone or control.
    Journal:Spine J. 2005 Jul-Aug;5(4):395-403

  20. Continuous low-level heatwrap therapy was shown to be effective for the treatment of acute, nonspecific LBP (Lower back Pain)
    Journal:Arch Phys Med Rehabil. 2003 Mar;84(3):329-34

  21. Wrist Pain
    Continuous low-level heat wrap therapy was efficacious for the treatment of common conditions causing wrist pain and impairment
    Journal:Arch Phys Med Rehabil. 2004 Sep;85(9):1409-16

  22. Long Lasting Relief
    Overnight use of heatwrap therapy provided effective pain relief throughout the next day, reduced muscle stiffness and disability, and improved trunk flexibility. Positive effects were sustained more than 48 hours after treatments were completed
    Journal:Arch Phys Med Rehabil. 2003 Mar;84(3):335-42

  23. Faster recovery with Exercise & Heat Therapy
    Recovery from acute lower back pain was faster when Heat Therapy was combined with exercise
    Journal: Spine 2005, 5, 395-403.

  24. Use of low level of continuous heat and Ibuprofen as an adjunct to physical therapy improves pain relief, range of motion and the compliance for home exercise in patients with nonspecific neck pain: A randomized controlled trial.

  25. Petrofsky JS, Laymon M, Alshammari F, Khowailed IA, Lee H.J Back Musculoskelet Rehabil. 2017 Mar 3; . Epub 2017 Mar 3.